Pronounced "She-Say-Doe," Shiseido is one of the oldest cosmetic companies in the world. Founded in 1872 by Yushin Fukuhara as Japan's first western-style pharmacy, the line has since proved itself as a true pioneer in the world of beauty. How did it start? In 1888, Shiseido introduced Japan's first toothpaste. Then, in 1897, the innovators made the shift from pharmaceuticals to cosmetics and debuted their oldest existing product, Eudermine, a skin softening lotion that is so advanced, it's still sold throughout the world today.